Which of the following describes a general indicator of CNS depressant use?

Drowsiness serves as a general indicator of CNS depressant use because these substances, which commonly include alcohol, benzodiazepines, and barbiturates, tend to slow down brain activity and depress the central nervous system. The sedation effect that results from these substances frequently leads to a state of drowsiness, lethargy, or fatigue.

In contrast, signs like increased wakefulness, rapid speech, and heightened reflexes are typically associated with CNS stimulants, not depressants. Stimulants elevate alertness, energy levels, and can lead to an increase in heart rate and activity, while CNS depressants result in reduced activity and sedation. Therefore, drowsiness is a clear and recognized symptom of CNS depressant use.