Which of the following characteristics defines a Schedule III drug compared to Schedule I and II?

A Schedule III drug is defined by a lower potential for abuse relative to Schedule I and II drugs. Schedule I drugs are classified as having a high potential for abuse and no accepted medical use, making them illegal under federal law. Schedule II drugs, while they have accepted medical uses, also carry a high potential for abuse that can lead to severe psychological or physical dependence.

In contrast, Schedule III drugs have accepted medical uses and a recognized lower potential for abuse. This classification reflects that while there can still be a risk of abuse and dependence, it is considered less severe than that of Schedule I or II substances. This characteristic allows for a level of regulation and accessibility in therapeutic applications, differentiating Schedule III drugs from more strictly regulated categories.

The other characteristics mentioned do not apply to Schedule III drugs. For instance, they can be legally prescribed, do not require a special license to obtain, and are not strictly illegal like Schedule I substances.