Which indicator is typically associated with high doses of inhalants?

High doses of inhalants are commonly associated with VGN, which stands for Vertical Gaze Nystagmus. This condition occurs when there is an involuntary movement of the eyes when a person is asked to look up or down. It is indicative of central nervous system depression and can be a direct result of the substances found in inhalants.

When someone is under the influence of high doses of these substances, their ability to focus and control eye movements is impaired, leading to the characteristic eye movement known as nystagmus. This is an important sign for law enforcement and medical personnel when assessing a person's level of intoxication due to inhalants. The other indicators mentioned, such as clear eyesight, normal alertness, and reflexive responses, do not typically correlate with inhalant use at high doses, as those would indicate a more normal state of functioning contrary to what one would observe in someone suffering from the effects of inhalants.